OB/GYN Clinical Alert – April 1, 2003
April 1, 2003
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International Collaborative Ovarian Neoplasm Trial 1 and Adjuvant ChemoTherapy In Ovarian Neoplasm Trial
The trial concluded that platinum-based adjuvant chemotherapy improved overall survival and recurrence-free survival at 5 years in this combined group of patients with early stage ovarian cancer defined by the inclusion criteria of the ICON1 and ACTION trials. -
Magnesium Sulfate and Nimodipine for the Prevention of Eclampsia
Magnesium sulfate is more effective than nimodipine for prophylaxis against seizures in women with severe preeclampsia. -
Treatment of Sexual Dysfunction After Menopause
In postmenopausal patients with sexual dysfunction, it is still unclear which, if any, therapy is indicated. -
Drug Treatments to Prevent Breast Cancer
Only tamoxifen has enough evidence to recommend it for the prevention of breast cancer, and its use is limited to very high-risk women with a low risk of side effects. -
Increased Risk of Breast Cancer with Estrogen-Progestin Therapy
Postmenopausal estrogen-progestin therapy increased the risk of breast cancer in a population-based cohort in Sweden, and estrogen-only did not. -
Radical Trachelectomy and Pelvic Lymphadenectomy with Uterine Preservation in the Treatment of Cervical Cancer
Radical trachelectomy combined with pelvic lymphadenectomy can be a feasible method of treatment for early-stage cervical cancer in women who want to preserve their fertility. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch: Warfarin Effectively Prevents Venous Thromboembolism
Warfarin Effectively Prevents Venous Thromboembolism; Vitamin D Reduces Osteoporotic Fractures; Adefovir Effective for Hepatitis B Treatment; Ibuprofen/Aspirin Study Revisited; ACE Inhibitors Favored in Cardiovascular Care; Digoxin Dosing and Heart Failure