OB/GYN Clinical Alert – November 1, 2003

November 1, 2003

• The WHI Reports on Fracture and Gynecologic Cancers 

  The Womens Health Initiative (WHI) reports that estrogen-progestin therapy reduces fractures, but the number of gynecologic cancers observed precludes a definitive statement on the risk of endometrial and ovarian cancers.

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• ‘It’s Déjà vu All Over Again’ *

  Weekly injections of alpha-hydroxyprogesterone caproate resulted in a substantial reduction in the rate of recurrent preterm delivery among women who were at particularly high risk for preterm delivery and reduced the likelihood of several complications in their infants.

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• External Version: Can We Spare Patients from a Cesarean Section?

  As pointed out in previous OB/GYN Clinical Alerts, about 1 in 4 patients in the United States are delivered by cesarean section, a procedure still classified as a major operation.

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• Pharmacology Watch: Generic Paxil Scheduled to Hit Market this Fall

  A generic form of paroxetine (PaxilGlaxoSmithKline) will soon be on the market. The drug marks the second SSRI antidepressant to go generic after fluoxetine (Prozac) last year.

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• Clinical Briefs in Primary Care Supplement

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