OB/GYN Clinical Alert – August 1, 2003
August 1, 2003
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Influence of Estrogen Plus Progestin on Breast Cancer and Mammography in Healthy Postmenopausal Women
In an intent-to-treat analysis, the use of conjugated equine estrogen combined with continuous medroxyprogesterone acetate by menopausal women increased the hazard ratio of invasive breast cancer to 1.24. -
Relationship Between Long Durations and Different Regimenes of Hormone Therapy and Risk of Brest Cancer
The data in this case-control study of combined estrogen plus progestin therapy revealed an increased risk of breast cancer, particularly invasive lobular tumor, regardless of whether the progestin component was taken sequentially or continuously. -
Perinatal Outcomes in Twins: The Effect of Placental Abruption
Birth weight discordancy of > 15% for same sex and > 30% for different sex confer greatest risk of adverse perinatal outcomes in the absence of abruption. -
Radiation Therapy With or Without Extrafascial Hysterectomy for Bulky Stage IB Cervical Carcinoma
Following radiation therapy, adjuvant extrafascial hysterectomy decreased the risk of relapse for patients with bulky stage IB cervical cancer without improving survival. -
Special Feature: Alternatives for Hot Flushing
The vasomotor flush is viewed as the hallmark of the female climacteric, experienced to some degree by most postmenopausal women. In the Massachusetts Womens Health Study, the incidence of hot flushes increased from 10% during the premenopausal period to about 50% just after cessation of menses. -
Pharmacology Watch: Nasally Administered Flu Vaccine Comes to United States
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Clinical Briefs in Primary Care Supplement