OB/GYN Clinical Alert – March 1, 2006
March 1, 2006
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A New Wrinkle in the Prevention of Preterm Delivery Through Cervical Cerclage
In the January issue of the American Journal of Obstetrics and Gynecology an article from Japan appeared that will shed new light on the practice of using cerclage in patients with short cervices. Over a 5-year period 16,508 had transvaginal ultrasound evaluations between 20-24 weeks. -
The Gaining Prominence of Chemotherapy in the Adjuvant Treatment of Advanced Endometrial Cancer
Advanced stage endometrial cancer represents a significant therapeutic challenge as it encompasses patients with a diverse spectrum of disease and recurrence risk. Currently, most patients are treated following primary surgical extirpation with a modality either directed at tumor residua or to a high-risk locale of recurrence. Either or both radiation therapy and chemotherapy have been used. -
Tibolone and Atherosclerosis
The Osteoporosis Prevention and Arterial Effects of tiboLone (OPAL) study was a 3-year, randomized, double-blind trial in 6 US centers and 5 European centers, treating 866 postmenopausal women with either 2.5 mg tiboLone daily, 0.625/2.5 mg daily of conjugated estrogens/medroxyprogesterone acetate, or placebo. -
Bladder Injury During Vaginal Hysterectomy After Cesarean Delivery
A medline search was conducted for comparisons of vaginal hysterectomy in patients with/without previous cesarean delivery. As might be anticipated, the studies were heterogeneous. For example, in one study, some cases had laparoscopic assistance. -
Risk-Reducing Surgery in Women with Lynch Syndrome has Merit
The Lynch Syndrome (hereditary non-polyposis colorectal cancer) is a cancer susceptibility syndrome highlighted by early age onset of cancers of the colon and rectum, endometrium, ovary, small bowel, ureter and renal pelvis. It is mediated via autosomal dominant transmission of germ-line mutations in DNA-mismatch repair genes. -
How are Fibromyalgia, Depression, and Sexual Dysfunction Related?
The authors sought to determine the relationship between psychiatric and sexual status of premenopausal women with fibromyalgia compared to a control group of healthy women. -
Pharmacology Watch: Treating Opioid-Dependent Patients with OAT
Long-Term Effects of Warfarin Use; Statins Multiple Benefits; FDA Actions -
Clinical Briefs in Primary Care supplement