Neurology Alert – November 1, 2004
November 1, 2004
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Vestibular Neuritis and Bell’s Palsy: Same Cause? Same Treatment?
Methylprednisolone significantly improves the recovery of peripheral vestibular function in patients with vestibular neuritis, whereas valacyclovir does not. -
Carotid Endarterectomy vs Stenting: When Randomized Becomes a Dirty Word
Among patients with severe carotid-artery stenosis and coexisting conditions, carotid stenting with the use of an emboli-protection device is not inferior to carotid endarterectomy. -
Functional MRI (fMRI) as a Replacement for the Wada Test in Evaluating Memory Function?
Although further technical improvements and prospective clinical validation are required, these results suggest that mesial temporal memory activation, detected by fMRI during complex visual scene encoding, correlates with post-surgical memory outcome, and supports the notion that this approach will ultimately contribute to patient management. -
A Major Advance in CT Angiography, Volumetric Computed Tomography (VCT)
VCT substantially improves imaging of vascularization in tumors and offers a promising tool for preclinical studies of tumor angiogenesis and antiangiogenic therapies. -
Possible Role of Retroviral Gene Expression in Multiple Sclerosis
Syncytins proinflammatory properties in the nervous system demonstrate a novel role for an endogenous retrovirus protein, which may be a target for therapeutic intervention. -
Neuropathy in Neurofibromatosis
Peripheral neuropathy in NF-1 patients is a marker for poorer prognosis and mandates heightened vigilance for malignancy and spinal cord complications. -
How Do Mutations in DJ-1 Cause Parkinson’s Disease?
Dopamine neurons derived from in vitro differentiated DJ-1 deficient embryonic stem cells showed decreased survival and increased sensitivity to oxidative stress. -
Does Deep Brain Stimulation Improve Sexual Well-Being in Parkinson’s Disease?
Deep brain stimulation of the subthalamic nucleus appears to affect sexual functioning in a small but positive way. Male patients with Parkinsons Disease, especially when younger than 60, appeared more satisfied with their sexual well-being over a short-term follow-up period. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch: The FDA and Merck Fielding Concerns About Vioxx
Merck announced on September 30th that it is voluntarily withdrawing rofecoxib (Vioxx) from the worldwide market.