Neurology Alert – June 1, 2004
June 1, 2004
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Next Generation Migraine Drugs?
Olesen and associates report on a phase II study of BIBN 4096 to evaluate the safety and efficacy of a first in class non-peptide, parenteral CGRP-receptor antagonist. -
Myasthenia Gravis 2004
Does prednisone, administered early in the course of ocular myasthenia, affect its progression to generalized disease? -
Lack of Inflammatory Pathology in Early Multiple Sclerosis Lesions
Barnett and Prineas describe the pathological and clinical findings in 12 patients with relapsing-remitting multiple sclerosis, who died shortly after the onset of a relapse. -
Assessment of the Risk of Stroke or Blindness in Giant Cell Arteritis
In order to identify risk factors for CNS ischemic complications at presentation and during follow-up, Nesher and associates reviewed the charts of 175 patients with giant cell arteritis diagnosed between 1980 and 2000 at 4 Jerusalem hospitals. -
Stroke During Cardiac Surgery: A Possible Opportunity for Prophylactic Neuroprotection?
Cardiac surgery may be complicated by ischemic stroke as well as more non-specific cognitive disturbances. Could prophylactic neuroprotective strategies be employed? -
Gynecologists Beware
New-onset leg weakness or numbness is a common cause for neurologic consultation following gynecologic surgery. -
Is Neuroimaging Needed to Assess Acute Oculomotor Nerve Palsies?
This paper reports the results of a prospective study of patients aged 50 years and older with acute isolated third, fourth, and sixth nerve palsies. -
Do Seizures in Older Adults Predict Stroke Risk?
Using data from the UK General Practice Research Database, Cleary and associates evaluated the hypothesis that late-onset (60-year-old subjects and older) seizures increase the risk of subsequent stroke. -
Pharmacology Watch: Missing Link Between Vaccines and Diabetes
A large cohort study from Denmark suggests no link between childhood vaccines and type 1 diabetes. -
Clinical Briefs in Primary Care Supplement