Neurology Alert – May 1, 2011
May 1, 2011
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First Successful Surgical Trial for Gene Therapy in Parkinson's Disease
A controlled surgical trial of glutamic acid decarboxylase gene therapy, targeting the subthalamic nucleus in advanced Parkinsons's disease, demonstrated statistically significant improvement in motor symptoms off medication in those receiving gene therapy compared with controls. -
Early Prediction of Long-Term Outcome After Traumatic Spinal Cord Injury
A composite score that combines age, motor power, and light touch perception can predict recovery of walking with great accuracy in patients with traumatic spinal cord injury. -
Flu Shots and Myasthenia Gravis
Seasonal flu and H1N1 vaccines are safe for patients with myasthenia gravis and should be administered. -
Decompressive Craniectomy for Severe Diffuse TBI
Decompressive craniectomy for severe diffuse traumatic brain injury and refractory intracranial hypertension (ICP) reduces ICP but increases unfavorable outcomes. -
Genetic Susceptibility to Fatal Rash from Carbamazepine? The Case for HLA Screening
Carbamazepine has been linked with severe forms of hypersensitivity reactions. As such, genome wide approaches to identify patients-at-risk have become increasingly important. -
Stroke Alert: A Review of Current Clinical Stroke Literature
Rotational vertebral artery syndrome (RVAS) is a rare syndrome usually caused by compression of the dominant vertebral artery in the neck with extreme head rotation to the contralateral side. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch
Anticholinergic drugs for COPD; pioglitazone for diabetes prevention; insulin degludec in Phase 3 trials; and FDA Actions.