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Neurology Alert – March 1, 2009
March 1, 2009
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The Calcitonin Gene-Related Peptide Receptor: A New Source of Acute Migraine Relief
Telcagepant, a new oral calcitonin gene-related peptide receptor antagonist, has similar efficacy and better tolerability for acute migraine headaches as compared to a triptan. -
Stroke Is Associated with Central Periodic (Cheyne-Stokes) Breathing
Sleep disordered breathing occurs in most acute stroke patients and may contribute to morbidity -
Congenital Myopathy 2009
Great progress has been made in identifying the underlying genetic defects in congenital myopathies. -
Alzheimer Immunotherapy Can Alter Vascular Amyloid
Although the active immunization trial was stopped because of severe side effects, autopsy studies revealed that soluble plaque amyloid moves to the perivascular spaces as an initial step before it is cleared from the brain. -
CNS Infections: An Indication for Continuous EEG Monitoring?
In this retrospective study, the authors describe the prevalence and significance of both electrographic seizures and periodic discharges in critically ill patients with central nervous system infections. -
Decreased Size of Acute Ischemic Stroke: An Additional Benefit from Chronic Warfarin Therapy?
Chronic treatment with warfarin, prior to presentation with an ischemic stroke, is associated with a significant decrease in infarct size. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch
FDA warning on topical anesthetics; antipsychotics increase sudden cardiac death; the step up vs step down debate; treating pain, fatigue, mood, and sleep in fibromyalgia; FDA Actions.