Neurology Alert – April 1, 2008

April 1, 2008

• Traumatic Brain Injury: A Modern Epidemic of "Shell Shock," Revisited

  Mild TBI may be associated with brain microhemorrhages and white matter disruption, even with mild or absent symptoms of a postconcussion syndrome.

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• Doxycycline Treatment for Multiple Sclerosis

  Addition of doxycycline to interferon-beta therapy in patients with relapsing-remitting multiple sclerosis might improve control of inflammatory lesions.

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• Neurologic Sequelae of Inflammatory Bowel Disease

  Neuropathic symptoms and signs occur in about one-half of patients with inflammatory bowel disease.

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• Cataplexy: A Laughing Matter?

  Functional MRI imaging in patients with narcolepsy supports the hypothesis of decreased hypothalamic activity with reduced orexin production.

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• An Enhanced Risk of Cancer from CT Scans

  There is an increased risk of future cancer as a consequence of performing repeated CT scans, and the younger the patient at the time of scanning, the greater the subsequent risk.

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• Can We Predict the Outcome of Bacterial Meningitis?

  The risk of adverse outcomes in bacterial meningitis can be estimated upon initial patient presentation using six clinical features.

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• Clinical Briefs in Primary Care Supplement

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• Pharmacology Watch

  Does erythropoietin worsen cancer death rates? Most hypothyroid patients can be replaced with levothyroxine alone without additional T3. Does aggressive control in type 2 diabetes save lives?

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