Neurology Alert – November 1, 2003
November 1, 2003
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Neurosarcoidosis: A Review
Sarcoidosis is a multisystem granulomatous disease most often affecting the lungs, eyes, skin, and liver, with neurological involvement in 5-10%. -
Topiramate for Painful Diabetic Neuropathy
Topiramate may soon legitimately be added to the list of Anticonvulsants useful for the control of painful diabetic peripheral neuropathy. -
Temporal Lobectomy: Emergent Psychopathology
Carran and colleagues describe the development of mania and depression in patients undergoing surgery for intractable epilepsy. -
Antifibrinolytics Do Not Improve Outcome After Subarachnoid Hemorrhage
Roos and associates reviewed the effect of antifibrinolytic treatment in patients with aneurysmal subarachnoid hemorrhage. -
Risks of Carotid Endarterectomy Reviewed
Bond et al have shown by metaanalysis that the classification of ischemic events into different categories such as ocular TIA, cerebral TIA, and cerebral infarction leads to differences in surgical operative risk and benefit. -
Has deCODE Really Decoded a Stroke Gene?
The most recent publication of the deCODE investigators from Iceland describes the steps they took to go from a linked chromosomal region to culprit gene. -
Clinical Features of MuSK-Positive Myasthenia Gravis
Among myasthenia gravis patients who are seronegative (SNMG) for acetylcholine receptor antibodies (AchR Ab), up to 70% demonstrate positivity for IgG antimuscle-specific kinase (MuSK) antibodies. How do they differ clinically from SNMG patients negative for both AchR Ab and MuSK Ab? -
MS and Stress: Role in Exacerbations
Buljevac and colleagues assessed whether life events that are perceived as stressful by patients themselves are associated with exacerbations. -
MS and Fatigue: Possible Role of Autonomic Dysfunction
This study corroborates a few earlier studies indicating that sympathetic vasomotor dysfunction may have a role in MS-related fatigue. -
Clinical Briefs in Primary Care Supplement
Insulin Plus Metformin vs Triple Oral Therapy in Type 2 Diabetes; ARB and ACE-I in Diabetic Nephropathy; Low-Glycemic Index Diets and Diabetes; Ultralow-Dose Estrogen and Bone in Older Women; Effect of Intensity of Oral Anticoagulation in Atrial Fibrillation; Patient Knowledge and Awareness of Hypertension -
Pharmacology Watch: Generic Paxil Scheduled to Hit Market this Fall
A generic form of paroxetine (PaxilGlaxoSmithKline) will soon be on the market.