– February 1, 2014
February 1, 2014
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Effect of Prophylactic Cranial Irradiation on Survival in Elderly Patients with Limited-Stage SCLC
Using the SEER database, this report examined 1926 patients aged ≥ 70 years who were diagnosed with limited-stage small cell lung cancer between 1988 and 1997.Choosing Myeloma Maintenance Therapy: Patient Choice
In a survey of consecutive myeloma patients from the Mayo Clinic on hypothetical constructs with varying expectations regarding overall survival benefit, toxicity, and financial burden, it was found that the majority of patients would not choose maintenance if toxicity was more than just mild and overall survival benefit was less than 1 year.Panitumumab-FOLFIRI: Effective Second-line Treatment for Metastatic Colorectal Cancer
A previously reported, industry-sponsored phase 3 trial showed improvements in progression-free survival, objective response, and a non-significant trend toward increased overall survival with panitumumab-FOLFIRI vs FOLFIRI alone for second-line wild-type KRAS metastatic colorectal cancer.Pelvic Radiation in Endometrial Cancer: Are We Cutting Off Our Nose to Spite Our Face?
Long-term complications, particularly secondary cancers, were significantly more common in patients receiving whole pelvic radiation (vs brachytherapy alone) for early-stage endometrial cancer.