– October 1, 2011
October 1, 2011
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Radiotherapy and Short-term Androgen Deprivation for Localized Prostate Cancer
In a large multi-institutional prospective trial conducted from 1994-2001, 1979 eligible patients (median age 70 years) with PSA < 20 were randomized to radiation therapy alone or radiotherapy plus 4 months of total androgen suppression starting 2 months before radiotherapy. -
Timing of Influenza Vaccination in Patients Receiving Chemotherapy
For patients in the midst of chemotherapy, there are little data on the most efficacious time to administer influenza vaccine. In a randomized study of 38 patients receiving FEC chemotherapy for adjuvant treatment of breast cancer, it is apparent that vaccination early (on day 4 of a 21-day cycle) provided better antibody response than when administered late in the cycle (day 16). -
Incidental Adrenal Mass
A 70-year-old man undergoing preoperative evaluation for abdominal aortic aneurysm surgery was noted to have a 3 cm mass in the right adrenal gland with heterogeneous texture but clear margins. -
Bendamustine-Rituximab as First-line Treatment for NHL Patients Over the Age of 80 Years
Fourteen elderly patients (median age 85 years) who were considered non-candidates for R-CHOP were treated first-line with a combination of bendamustine and rituximab. Of these, 7 achieved a complete response and 2 achieved a partial response. Toxicity was minimal. Although promising, these results need to be confirmed in larger studies. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch
Apixaban could soon join the anticoagulation market; Chinese herbs for flu; chronic medication and discontinuation after hospitalization; and FDA actions.