– March 1, 2008
March 1, 2008
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Prophylactic Cranial Radiation Revisited: Significant Change in Cognitive Function Not Found
Prophylactic cranial radiation (PCI) has been shown to reduce the incidence of CNS metastases and prolong survival for patients presenting with limited-stage small cell lung cancer (SCLC). However, concern that such treatment results in cognitive decline has tempered enthusiasm, but this claim has not been satisfactorily addressed. -
Beta-2 Microglobulin in AML
In a large series of acute myelogenous leukemia patients, elevated serum beta-2 microglobulin was found to be an independent negative prognostic factor with regard to overall survival, but was significant only for those over the age of 60 years. -
Immune Thrombocytopenia and CLL
Immune thrombocytopenia is a problematic but poorly characterized complication of chronic lymphocytic leukemia. The authors propose a definition for immune thrombocytopenia in CLL that included a 50% drop in platelet count and adequate marrow megakaryocytes in the absence of chemotherapy or other causes. -
Birth Control Pills and Ovarian Cancer Prevention
A prior use of oral contraceptives has been known to have an inhibitory effect on ovarian cancer development. -
Pharmacology Watch
Stop smoking drug Chantix rates stronger warning from FDA; Type 2 diabetes surgery on the way?; Vytorin study inconclusive; Influenza A virus found resistant to Tamiflu; FDA actions. -
Clinical Briefs in Primary Care Supplement