– January 1, 2003
January 1, 2003
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Second Malignancy after Treatment of Hodgkin’s Disease: The Influence of Treatment, Age, and Follow-up Time
Synopsis: Combination chemotherapy and extensive radiotherapy introduced in the late 1960s greatly improved survival rates in Hodgkins disease (HD), but increased risk of second cancer was recognized from the early 1970s. -
Beta-2-Microglobulin: Prognostic Indicator in Early Stage Hodgkin’s Disease
Synopsis: Of 217 consecutive Hodgkins disease patients seen at M.D. Anderson with Stage I or II disease who received chemo- and radiation therapy, 12 had elevated b2M (> 2.5 mg/L). There was a trend for reduced relapse-free survival for those with elevated levels, and a significant correlation with reduced overall survival. Thus, an inexpensive and widely available laboratory measure might provide useful prognostic information in patients with Hodgkins disease. -
Follow-up Survival after Early Stage Laparoscopy in Women with Endometrial Cancer
Eltabbakh retrospectively reviewed women presenting with clinical stage I endometrial cancer (according to the 1988 FIGO staging) at the University of Vermont. Women treated with laparoscopic surgery were compared with those treated with laparotomy with regard to their characteristics, surgical procedure, treatment, surgical stage, histology, tumor grade, and recurrence-free and overall survival. -
Cyclin E and Survival in Patients with Breast Cancer
Synopsis: The hazard ratio for death from breast cancer for patients with high total cyclin E levels as compared with those with low total cyclin E levels was 13.3 to about 8 times as high as the hazard ratios associated with other independent clinical and pathological risk factors, including axillary node status. -
Outcomes of Endometrial Cancer Patients Undergoing Surgery With Gynecologic Oncology Involvement
Synopsis: Involvement of a gynecologic oncologist at the time of primary surgery for endometrial cancer was associated with comparable outcomes in both the university and community hospital setting. -
Alcohol and Hormone Therapy Increase the Risk of Breast Cancer
Synopsis: The Nurses Health Study reports an increased incidence of breast cancer with daily alcohol consumption, hormone therapy, and an additive effect with greater drinking. -
Pharmacology Watch: FDA Approves Claritin For OTC Use For Seasonal Rhinitis
After years of legal wrangling, the FDA has approved loratadine (Claritin, Schering-Plough) as an over-the-counter (OTC) product for the treatment of seasonal rhinitis. -
Clinical Briefs in Primary Care Supplement