– November 1, 2002

November 1, 2002

• Dose Intensive and Dose Dense CHOP Regimens

  The October 2002 issue of the Annals of Oncology contains 2 articles and an editorial describing a dose-dense and dose- intense CHOP regimen in hopes to optimize outcome.

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• Hormone Replacement Therapy Formulations and Risk of Epithelial Ovarian Cancer

  Sit and Associates from the University of Pittsburgh assessed the association between the use of Hormone Replacement Therapy (HRT) and the risk of invasive epithelial ovarian cancer in women participating in a population-based, case-control study conducted in the Delaware Valley from 1994 to 1998.

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• Stage III Colon Cancer: The Importance of the Number of Nodes

  Traditionally, stage III colon cancer is defined on nodal involvement independent of tumor size (eg, T1-T4). However, recent reports have suggested that there is a heterogeneous survival pattern within stage III colon cancer patients, when examined in the context of T and N categories.

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• The IBIS-1 Breast Cancer Prevention Trial: Initial Results

  The International Breast Cancer Intervention Study (IBIS) performed by a collaborative group from the United Kingdom, Australia, New Zealand and some additional European countries initiated a trial in 1992 to determine the role of Tamoxifen in the prevention of breast cancer in women at high risk.

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• Menopausal Hormone Replacement Therapy and Risk of Ovarian Cancer

  Between 1973 and 1980, the American Cancer Society and the National Cancer Institute conducted the Breast Cancer Detection Demonstration Project (BCDDP). More than one quarter of a million women were involved in this study.

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• Clinical Briefs in Primary Care Supplement

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