Internal Medicine Alert – January 30, 2019

January 30, 2019

• Prostatectomy Beats Watchful Waiting in Men Diagnosed With Prostate Cancer in the 1990s

  In men with prostate cancer diagnosed in the 1990s (primarily by digital rectal exam), researchers found that radical prostatectomy offered an average survival benefit of 2.9 years over watchful waiting.

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• Low-Carbohydrate Diet Increases Energy Expenditure

  Consistent with the role of insulin and carbohydrate intake, a low-carbohydrate diet increases energy expenditure and facilitates the maintenance of weight loss.

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• Helicobacter pylori: A Mini Primer

  Although the prevalence of Helicobacter pylori seems to be decreasing in the United States, at least in higher socioeconomic strata, it remains a problem for lower-income groups, travelers to developing countries, and the rest of the world.

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• Alcohol Use: No Safe Level

  A systematic analysis of data from the Global Burden of Disease Study 2016 on alcohol-linked disorders and patterns of alcohol use over 25 years worldwide found there is no safe level of alcohol consumption.

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• Should Acute Appendicitis Be Managed Without Appendectomy?

  A retrospective cohort study that used national insurance claims data revealed patients with acute appendicitis who were treated nonsurgically experienced higher rates of complications and higher overall care costs.

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• Prucalopride Tablets (Motegrity)

  Prucalopride is indicated for the treatment of chronic idiopathic constipation in adults.

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