Internal Medicine Alert – April 30, 2018
April 30, 2018
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Mefloquine: Still Effective and Still Safe for Malaria Chemoprophylaxis
Mefloquine is known as an effective agent for malaria chemoprophylaxis. However, concerns about serious adverse effects have limited its use. Now, a careful review of data suggests that fatal outcomes related to mefloquine prophylaxis are very rare.
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Hospital Ice Machines Contaminated With Bacteria
Requiring staff to cleanse their hands with alcohol hand gel prior to using an ice machine and directing housekeeping personnel to perform more frequent machine cleaning may improve situation.
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Pre-existing Health Determines Quality of Life, Physical Symptoms After ICU Discharge
The authors of this nested cohort study within a randomized, controlled trial of ICU survivors requiring > 48 hours of mechanical ventilation found that pre-existing comorbidity was the main determinant of long-term health-related quality of life.
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Tildrakizumab-asmn Injection (Ilumya)
Tildrakizumab-asmn is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
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Clinical Briefs
In this section: treating obstructive sleep apnea; influenza and myocardial infarction; and a promising Zika treatment.