Internal Medicine Alert – January 15, 2018
January 15, 2018
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Studies Find Cognitive Decline Reversible, Even if Patients Are ApoE4 Positive
Insulin resistance is associated with cognitive decline and Alzheimer’s disease. Patients who are positive for the apolipoprotein E4 gene are at increased risk for Alzheimer’s disease. This risk may be reversed by treating insulin resistance.
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L-methylfolate for Bipolar Disorder
L-methylfolate improves some symptoms in major depression in people with type 1 bipolar disorder.
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Newer Guidelines for Influenza Testing This Season
The California Department of Public Health and the CDC have recommended that, regardless of the results of prior rapid influenza testing, empiric therapy with a neuraminidase inhibitor should be administered promptly to patients hospitalized with influenza-like illness or suspected influenza.
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Travelers Unaware of the Need for Pre-travel Vaccinations
Outbreaks of measles continue to occur in the United States, mostly because of imported cases. More than half of these occur as the result of inadequately vaccinated returning U.S. travelers who acquire measles infection abroad.
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Buprenorphine Extended-release Injection (Sublocade)
Buprenorphine extended-release injection is indicated for the treatment of moderate-to-severe opioid use disorder in patients who have initiated treatment with a transmucosal buprenorphine-containing product, followed by dose adjustment for a minimum of seven days.
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Clinical Briefs
In this section: using diuretics in heart failure patients; sexual dysfunction in patients with diabetes; and treating subtle gastrointestinal symptoms.
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How Many Conduction Defects?
The ECG and long lead II rhythm strip in the figure with the article was obtained from a 58-year-old man who was admitted to the hospital with chest pain and weakness. How would you interpret the tracing? How many different types of conduction disturbances can you identify?