Internal Medicine Alert – October 15, 2015
October 15, 2015
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Intensification of Oral Therapy for Type 2 Diabetes
ABSTRACT & COMMENTARY: It may not be relevant to primary care physicians. Here's why.
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Nutrition Therapy for Hypertension Using the Nitric Oxide Pathway
Daily one-time ingestion of inorganic nitrate from beet juice consistently lowered blood pressure in hypertensive patients by an amount comparable to single-drug therapy.
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Vitamin D and Diabetic Neuropathy
Vitamin D deficiency may exacerbate the clinical manifestations of diabetic neuropathy, and supplementation with vitamin D3 may be beneficial.
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Evolocumab Injection (Repatha)
Evolocumab is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in patients who require additional lowering of LDL-C.
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Clinical Briefs
In this section: reversing the anticoagulant effect of dabigatran; considering the likelihood of occult cancer causing unprovoked deep venous thrombosis; and cardiovascular autonomic neuropathy occurs earlier in type 2 diabetes.
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ECG Review: A 43-Year-Old Man with Atypical Chest Pain