Internal Medicine Alert – May 30, 2015

May 30, 2015

• Risk of NSAID Use in Patients Receiving Antithrombotic Therapy After Myocardial Infarction

  The use of NSAIDs was associated with increased risk of bleeding and excess thrombotic events, even after short-term treatment.

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• Utility of the New Cholesterol Guidelines

  The risk:benefit ratio is much better for moderate- than high-intensity statins.

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• Clindamycin vs. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Infections

  Cure rates did not differ between the treatments and rates of adverse events were similar in the two groups.

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• Ivabradine Tablets (Corlanor ^®)

  Ivabradine's effect in reducing heart rate, by acting on the SA node, was most prominent at a higher heart rate, thus minimizing the risk of bradycardia.

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• Clinical Briefs

  This article covers the following topics: the saga of homocysteine and vasculopathy; roflumilast for acute exacerbations in COPD; and treatment of OSA reduces risk of repeat revascularization after PCI.

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