Internal Medicine Alert – February 28, 2014

February 28, 2014

• An Evidence-Based Insulin Intensification Regimen

  This study provides clinicians with valuable guidance on a technique by which insulin therapy may be intitiated and intensified using a safe, timely, and rational therapeutic approach.

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• Optic Disc Cupping and Cognitive Decline: Three-year Prospective Study Demonstrates Association

  This long-term epidemiological study shows an association between glaucoma and Alzheimer's disease. Cup to disc ratio, but not elevated intraocular pressure, is a risk factor for dementia.

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• Is Atrial Fibrillation Associated with Silent Cerebral Emboli?

  In this study comparing the prevalence of silent cerebral ischemia (SCI) and cognitive performance in patients with paroxysmal and persistent atrial fibrillation (AF) and controls in sinus rhythm, the authors concluded that patients with AF had more SCI and worse cognitive function than matched controls in sinus rhythm.

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• New Clinical Practice Guidelines for Preventing Heart Disease and Stroke

  The American College of Cardiology and the American Heart Association released new guidelines for preventing heart disease and stroke. Dr. Crawford provides expert opinion and commentary on why these new guidelines are so important.

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• Pharmacology Update: Conjugated Estrogens and Bazedoxifene Tablets (Duavee®)

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