Internal Medicine Alert – August 15, 2007
August 15, 2007
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Effects of High and Low Dose Atorvastatin on Major Cardiovascular Events in Patients with Stable Coronary Heart Disease
Compared to patients over the age of 65 years who were receiving 10 mg of atorvastatin daily, the elderly patients who received 80 mg daily experienced significantly reduced major cardiovascular and coronary events ... -
Dietary Intake and Prognosis after Breast Cancer
Patients with early breast cancer did not have fewer recurrences of cancer or improved mortality after eating a diet rich in vegetables and fruit and low in fat. -
Retinol Rejuvenation
Application of vitamin A to naturally aged skin reduced fine wrinkling -
Temsirolimus Injection (Torisel™)
The FDA has approved the first mTOR inhibitor for the treatment of advance renal cancer. Temsirolimus is a more water soluble ester of sirolimus and the latter is the principal active metabolite. -
Clinical Briefs By Louis Kuritzky, MD
The recent indication in an article by Nissen, et al (N Engl J Med. 2007;356:2457-2471) that rosiglitazone (ROSI) might actually increase cardiovascular (CV) risk was met with surprise and dismay by many clinicians and their patients alike. -
ECG Review: A Sensation in the Chest
The ECG in the Figure was obtained from a 59-year old man with hypertension. He was admitted to the hospital to rule out acute infarction because of an "unpleasant sensation" in his chest. -
Pharmacology Watch
SSRIs are associated with a low rate of birth defects according to 2 new studies in the New England Journal of Medicine. SSRIs are often taken by women in their childbearing years, but the risk of birth defects has been unclear.