Internal Medicine Alert – May 15, 2011
May 15, 2011
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Screening for Prostate Cancer: A Double-Edged Sword
In a large, randomized, controlled trial, screening for prostate cancer did not have a significant effect on mortality from prostate cancer after 20 years of follow-up. -
Disappearing Vitamin D?
Plasma concentrations of 25-hydroxyvita-min D [25(OH)D] decrease after an inflammatory insult such as knee surgery and, therefore, are unlikely to be a reliable measure of 25(OH)D status in patients with evidence of a significant inflammatory response. -
Aspirin and Gastrointestinal Bleeding
The use of low-dose aspirin is associated with an almost two-fold increase in the risk of upper gastrointestinal bleeding compared with nonuse and this risk is further increased when low-dose aspirin is combined with clopidogrel, oral anticoagulants, nonsteroidal anti-inflammatory drugs, or high-dose oral corticosteroids. -
Vandetanib Tablets (Zactima™)
A tyrosine kinase inhibitor has been approved for the treatment of medullary thyroid cancer (MTC). -
Clinical Briefs by Louis Kuritzky, MD
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ECG Review: Anything Acute Going On?
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Pharmacology Watch
Anticholinergic drugs for COPD; pioglitazone for diabetes prevention; insulin degludec in Phase 3 trials; and FDA Actions.