Internal Medicine Alert – April 30, 2009

April 30, 2009

• Statins in Primary Prevention of Cardiovascular Disease — Are We Ready?

  Use of statins as primary prevention in healthy people with elevated high-sensitivity C-reactive protein without hyperlipidemia may reduce the incidence of major cardiovascular events.

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• Antibiotics for Diverticulitis: Pick Your Route of Delivery

  Oral antibiotics were not found to be inferior to intravenous antibiotics in the treatment of clinically diagnosed acute diverticulitis.

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• Accuracy and Value of 64-Slice Coronary Computed Tomographic Angiography

  Compared with invasive coronary angiography, coronary computed tomographic angiography demonstrated high diagnostic accuracy for detection of obstructive coronary stenosis and a 99% negative predictive value.

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• Oxybutynin Chloride 10% Gel (Gelnique™)

  A new transdermal formulation of oxybutynin has been approved for the treatment of overactive bladder. Oxybutynin gel is marketed by Watson Pharmaceuticals as Gelniqueä.

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• Clinical Briefs By Louis Kuritzky, MD

  Most type 2 diabetics (DM2) who undergo bariatric surgery enjoy a prompt reversal or at least a substantial diminution of their dysglycemia.

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