Internal Medicine Alert – March 15, 2009

March 15, 2009

• Boning Up: Mortality Risk Associated with Fractures

  In older women and men, all low-trauma fractures were associated with increased mortality risk for at least 5 years. Subsequent fracture increased that risk.

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• Priming the Pump of a Leaky Gut

  This is the first study documenting that a PPI compromises the mucosal barrier function of the upper GI tract.

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• Eltrombopag Tablets (Promacta®)

  Eltrombopag is a thrombopoietin (TPO) receptor agonist approved by the FDA for the treatment of thrombocytopenia.

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• Clinical Briefs By Louis Kuritzky, MD

  The women's health initiative (WHI) provided convincing evidence that the use of estrogen plus progesterone (E+P) in postmenopausal women is associated with an increased risk of breast cancer.

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• ECG Review: What Happened in the Past?

  The ECG shown above was a baseline tracing obtained during the initial visit with a new primary care provider. How would you interpret the tracing? What do you suspect happened in the past?

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