Internal Medicine Alert – July 30, 2010
July 30, 2010
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Should We Use Colchicine for Acute Gout, and If So, How Much?
A randomized controlled trial showed that low-dose colchicine, 1.2 mg initially followed by 0.6 mg at 1 hour, was equally effective with fewer side effects as high-dose colchicine, eight 0.6 mg pills over 6 hours. The < 40% response rate with 23% getting diarrhea in the low-dose group calls into question whether colchicine is the superior choice over NSAIDs for acute gout. -
Where There's a Wheel, There's a Way
The more bike riding a premenopausal women does, the less likely she is to gain weight. -
Effects of Fibrates on Cardiovascular Outcomes
Fibrates can reduce the risk of major cardiovascular events predominantly by prevention of coronary events, and might have a role in treating individuals who are at especially high risk of cardiovascular events and in those with combined dyslipidemia. -
Two Streams Merge into One Mighty River?
Combining extended physical therapy and high-dose cholecalciferol can reduce two different complications of hip fracture: falls and hospital readmission. -
Everolimus Tablets (Zortress®)
Everolimus, a derivative of sirolimus, is a mammalian target of rapamycin (mTOR) inhibitor. -
Clinical Briefs by Louis Kuritzky, MD
Male sexual dysfunction is well recognized as a consequence of diabetes.