Internal Medicine Alert – October 30, 2005
October 30, 2005
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Excessive Daytime Sleepiness in a General Population Sample: The Role of Sleep Apnea, Age, Obesity, Diabetes and Depression
Complaints of sleepiness are common in those being treated for depression, in diabetics, in the obese, in smokers, and in those with sleep apnea. -
NSAIDs May Cause Urinary Retention
A 3.3-fold increase in acute urinary retention was found in new male users of nonsteroidal anti-inflammatory drugs (NSAIDs) compared to non-users in a large primary care database from the Netherlands. The risk for all male NSAID users was 2.3-fold greater. -
The Risk Predictive Value of the Coronary Artery Calcification Score in Middle-Aged Healthy Men
In middle-aged, asymptomatic men, the presence of coronary artery calcification proved to have substantial, cost-effective, independent prognostic value that was incremental to measured coronary risk factors in its ability to predict incident coronary artery disease. -
Proton Pump Inhibitors Reduce the Bioavailability of Dietary Vitamin C
Even a short course of omeprazole reduces plasma vitamin C levels in healthy volunteers, and this effect would be expected to be magnified in H. pylori-positive individuals who have low pre-treatment vitamin C levels. -
Pharmacology Update: Zolpidem Tartrate Extended Release Tablets (Ambien CR)
The FDA has approved an extended-release form of zolpidem. The drug delivery system consists of a coated 2-layer tablet, one releases the drug immediately and the other provides a slower release. Zolpidem extended-release (zolpidem ER) is marketed by Sanofi-Synthelabo as Ambien CR. -
Clinical Briefs By Louis Kuritzky, MD
Are NSAIDs Different in the CHF Impact?; Treatment of HTN and Cognitive Function: SCOPE; Impact of Job and Marital Strain on BP