Internal Medicine Alert – July 15, 2003
July 15, 2003
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Risk Factors in Sleep-Disordered Breathing
Over a 5-year period, the incidence of developing sleep-disordered breathing (AHI > 5 events/hr) is about 37%, about 7% per year. With aging, male gender and body mass index (BMI) lose importance as risk factors for obstructive sleep apnea. -
Choosing the Right Starting Dose of Warfarin
A warfarin initiation nomogram that uses 10 mg as a starting dose achieves a therapeutic INR more rapidly than one using a 5-mg starting dose. -
Prospective Study of Alcohol Consumption and Risk of Dementia in Older Adults
Compared with abstention, consumption of 1-6 drinks weekly of alcoholic beverages was associated with a lower risk of dementia among adults older than 65 years. -
Pharmacology Update: Gefitinib Tablets (Iressa — AstraZeneca)
The FDA recently approved gefitinib, an inhibitor of tyrosine kinase activity of the epidermal growth factor receptor, for the treatment of non-small-cell lung cancer. -
Clinical Briefs
Rapid Magnetic Resonance Imaging vs Radiographs for Patients with Low Back Pain; Effectiveness of Anticholinergic Drugs Compared with Placebo in the Treatment of Overactive Bladder; A Randomized Trial of a Low Carbohydrate Diet for Obesity -
ECG Review: The QRS Complex in Lead V2
The ECG in the Figure was obtained from a 73-year-old man with documented coronary disease and heart failure. He now presents with a 10-day history of dyspnea. How would you interpret his ECG? -
Attention Readers
Thomson American Health Consultants is happy to announce that we are opening up our Primary Care Reports author process to our readers. A biweekly newsletter with approximately 5000 readers, each issue is a fully referenced, peer-reviewed monograph.