Infectious Disease Alert – September 1, 2020
September 1, 2020
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The COVID-19 Pandemic: What Comes Next? Lessons from Seasonal Coronaviruses
In temperate regions other than China, human seasonal coronaviruses circulate most heavily during the winter months, overlapping with influenza and respiratory syncytial virus — and this may be the eventual pattern for SARS-CoV-2.
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Dexamethasone for COVID-19 Inpatients Requiring Oxygen
Dexamethasone administration is associated with reduced 28-day mortality in oxygen-requiring COVID-19 patients, including those receiving mechanical ventilation.
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Repeat Infections with Endemic Coronaviruses and Possible Implications for COVID-19
Repeat infection with endemic seasonal coronavirus occurs commonly and raises concerns about immunity to SARS-CoV-2 as well as about the efficacy of vaccines in the protection against infection due to this virus.
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Respiratory Syncytial Virus — Effective Prevention Still Needed
Prevention of respiratory syncytial virus infection is needed but challenging. New studies show some favorable effectiveness on infant outcomes with both vaccination of healthy pregnant women and passive single-dose immunization of prematurely born babies.
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A Novel Rifabutin-Containing Combination Regimen Is Effective for Eradicating H. pylori Infection
A Phase III, randomized, controlled trial found a significantly higher eradication rate for H. pylori with a 14-day regimen of rifabutin, amoxicillin, and omeprazole compared to 14 days of amoxicillin and omeprazole.
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Respiratory Syncytial Virus — Not Just a Disease of Children
Respiratory syncytial virus is a significant cause of morbidity and mortality in the elderly.
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Infectious Disease Alert Updates
Things Do Not Always Go Better with Cola; ‘Hygiene Theater’; Geodynamics of COVID-19 in Brazil