Infectious Disease Alert – February 1, 2020
February 1, 2020
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Ebola in Democratic Republic of the Congo: Confronting Potential Disaster
The second largest outbreak of Ebola virus infection has come under control.
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Preventing Ebola Virus Infection
In a scientific/public health triumph, the first vaccine for the prevention of Ebola virus infection has been approved. If administered prior to 10 days after exposure, its protective efficacy is 100%.
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Treating Ebola Virus Infection
Two monoclonal antibody preparations have been demonstrated to significantly reduce mortality in patients with Ebola virus infection.
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Impact of Infectious Disease Consultation for Candidemia
A retrospective cohort study found that infectious disease consultation for patients with candidemia resulted in lower 90-day mortality. This was likely a result of strong adherence to guideline- and evidence-based management and the low number of patients who were not treated.
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Tafenoquine for Malaria Prevention and Relapse Treatment
Tafenoquine is effective for the prevention of all species of malaria and can be used to prevent relapse of Plasmodium vivax and Plasmodium ovale. G6PD status should be evaluated prior to use.
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Pneumonia Outbreak in China
A cluster of cases of pneumonia apparently caused by a novel coronavirus has emerged in China.
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Fever of Unknown Origin Due to Cat Scratch Disease
Disseminated cat scratch disease may present as a fever of unknown origin.
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Feeding the Microbiota: Complementary Foods Enhance Recovery in Malnourished Children by Modulating the Gut Microbiota
In a series of studies in gnotobiotic animals and malnourished children, incomplete recovery from malnutrition is associated with immature gut microbiota, and complementary foods directed to enhance microbiotal maturity improved recovery from malnutrition.
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Infectious Disease Alert Updates
Lyme Carditis: Any AV Block of Concern; Syphilis Screening in Pregnancy a Must; Deferring INH Until Postpartum in HIV-Positive Women