Infectious Disease Alert – April 1, 2018
April 1, 2018
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Neuroimaging Before Lumbar Puncture?
The investigators retrospectively evaluated ESCMIID, IDSA, and Swedish guidelines for neuroimaging in 815 adults with acute bacterial meningitis. Swedish guidelines omit altered mental status and immunosuppression as indications for imaging prior to lumbar puncture. Adherence to Swedish guidelines resulted in decreased mortality and more favorable outcomes.
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SIRS Criteria vs. qSOFA for Predicting Short-term Mortality From Sepsis
A meta-analysis that included 38 studies found the SIRS criteria had a higher sensitivity than qSOFA in predicting short-term mortality from sepsis. SIRS criteria remain useful as a screening tool for sepsis and as a prompt to initiate diagnostic work-up and treatment.
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Refugee Screening
Screening and potential treatment of refugees prior to travel to the United States effectively reduces the burden of infection.
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Influenza Vaccine: High Dose or Standard Dose?
High-dose inactivated influenza vaccine was superior to standard-dose vaccine in providing protection against influenza or pneumonia-associated hospitalizations.
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Adjuvanted Recombinant Hepatitis B Vaccine (Heplisav-B)
Heplisav-B is a new hepatitis B vaccine approved by the FDA in November 2017.
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Infectious Disease Alert Updates
Online Sex and Sexually Transmitted Diseases; Swingers Come Out; HIV-positive Patients Require Hepatitis B Vaccine