Infectious Disease Alert – October 1, 2011
October 1, 2011
View Issues
-
Abstract & Commentary: Candida Chorioretinitis and Endophthalmitis
Oude Lashof and colleagues examined the incidence and outcomes of patients with ocular involvement in a randomized, clinical trial comparing treatment of non-neutropenic patients with candidemia with either voriconazole or amphotericin B followed by fluconazole. -
Abstract & Commentary: Frequent Detection of Cytomegalovirus in Stillbirths
A total of 130 singleton stillbirths from a single institution in Australia, from January 2005 through December 2006, of > 20 weeks gestation with no cause of death and with available formalin-fixed, paraffin-embedded tissues were examined by multiplex PCR for 19 infectious agents, and by immunohistochemistry for human cytomegalovirus (CMV). -
Abstract & Commentary: Azithromycin Restores Chloride Efflux in Cells of Cystic Fibrosis Patients
Two human cystic fibrosis (CF) bronchial epithelial cell lines and one CF human primary epithelial cell line in culture were treated with AZM at 10 µg/mL. -
Fidaxomicin for CDI in Patients Who Continue Concomitant Antibiotics: Arrival of a Superior Treatment Option?
CDI can be a difficult-to-manage complication of antibiotic therapy. Although it is preferable to discontinue the inciting antibiotic when CDI occurs, this is not always possible given that many patients have serious infections, which require ongoing antibiotic therapy. -
Abstract & Commentary: Activation of HIV by STI Pathogens
The authors conducted a series of experiments in which HIV-1 transfected 1G5 T cells were exposed to either a series of known long terminal repeat (TLR) ligands (FimH/TLR-4, flagellin/TLR-5, and poly I:C/TLR-3) or STI pathogens (HSV-1, HSV-2, and N. gonorrhoeae). -
Abstract & Commentary: Imported Pediatric Malaria
A retrospective review of pediatric malaria at a Washington, DC, children's hospital identified 98 cases over 8 years (1999-2006). Their mean age was 9.6 years. -
Abstract & Commentary: Strongyloidiasis in a Patient with HTLV-1 Infection
A 58-year-old Liberian-born woman was in excellent general health, living and working in a large academic medical center in Rhode Island for more than 20 years, when she developed nonspecific gastrointestinal symptoms and underwent endoscopy, which revealed Strongyloides stercoralis larvae on a duodenal biopsy in March 2010. -
Updates By Carol A. Kemper, MD, FACP
The increasing sophistication of molecular tools is allowing for the discovery of all kinds of novel strains of bacteria; witness the multiple new strains of Rickettsia discovered around the world. -
Pharmacology Watch: Apixaban is Heating Up the Anticoagulation Market
In this issue: Apixaban could soon join the anticoagulation market; Chinese herbs for flu; chronic medication and discontinuation after hospitalization; and FDA actions. -
Clinical Briefs in Primary Care supplement