Infectious Disease Alert – April 1, 2011

April 1, 2011

• Abstract & Commentary: Cephalexin vs. Clindamycin for Pediatric Skin Infections — Perhaps Drainage Is All That's Needed

  Two hundred patients from 6 months to 18 years of age with uncomplicated purulent SSTIs not requiring hospitalization were enrolled from 2006 through 2009.

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• Abstract & Commentary: Exposure to Environment Micro-organisms and Childhood Asthma

  Two separate, cross-sectional studies involving 6,843 and 9,668 children 6-13 years of age in South Germany randomly compared children living on farms with reference groups for the prevalence of asthma relative to the exposure to and diversity of indoor microorganisms.

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• Abstract & Commentary: STD Management — What's New?

  The latest iteration of the CDC guidelines on the treatment of STDs was finally published at the end of 2010 after finishing a process that began in 2008.

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• Abstract & Commentary: The Enigma of Bedbugs

  A group of investigators in France undertook an exhaustive review of bedbugs and found evidence of them in the tombs of Egypt 3,500 years ago.

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• Abstract & Commentary: Norovirus — It's Here to Stay

  Ten years after their original publication, the Centers for Disease Control and Prevention (CDC) has updated their recommendations for the prevention of norovirus infection and the management of outbreaks due to this non-enveloped, single-stranded RNA member of the Calciviridae family.

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• Abstract & Commentary: Orbital Cellulitis in Children

  A retrospective chart review of all patients admitted to a tertiary care children's hospital in Denver between 2004 and 2009 with orbital infections confirmed by CT scan was performed.

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• Brief Report: Once-Daily Pill Yields Higher ART Adherence

  Even HIV-infected individuals who have the greatest challenges in adhering to their antiretroviral therapy (ART) can achieve high adherence on a regimen of one pill taken daily, research shows.

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• Updates By Carol A. Kemper, MD, FACP

  Community acquired pneumonia "bundles" often include the use of the pneumococcal urinary antigen assay, but how useful is it for streamlining antibacterial use?

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• Pharmacology Watch: Apixaban and Rivaroxaban Near Approval for Nonvalvular AF

  In this issue: Apixaban and rivaroxaban near approval for nonvalvular atrial fibrillation; fidaxomicin for C. difficile infections; guideline for intensive insulin therapy; and FDA Actions.

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• Clinical Briefs in Primary Care supplement

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