Infectious Disease Alert – April 1, 2012
April 1, 2012
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Abstract & Commentary: Changing Epidemiology of Bacteremia in Infants
A retrospective analysis was conducted of all blood cultures collected on full-term (>=37 weeks) previously healthy infants presenting for care from 1 week to 3 months of age in a large California healthcare system over 5 years (2005-2009). -
Abstract & Commentary: Validation of Self-Swabbing for Flu Infections in the Community
Hong Kong investigators conducted 2 separate community studies using careful face-to-face instructions to potentially influenza infected patients. Sterile nasal swabs were rotated around the anterior nares. -
Special Feature: Appropriate Dosage of Vancomycin in End-Stage Renal Disease Patients Requiring Intermittent Hemodialysis
Infection is the second leading cause of death in hemodialysis patients, with mortality rates ranging from 12-36% in this vulnerable population. -
Readers Write: Itraconazole and adrenal function
In a recent discussion of a clinical case in the New England Journal of Medicine, the authors correctly indicate itraconazole is recommended for all but the most severe cases of disseminated histoplasmosis (when amphotericin B is used). -
Abstract & Commentary: Treating VAP: The Importance of Getting Initial Antibiotic Coverage Right
This study was a secondary analysis of data from an earlier randomized clinical trial comparing one antibiotic vs two (meropenem alone or meropenem plus ciprofloxacin) as early empiric therapy for ventilator-associated pneumonia (VAP). -
Abstract & Commentary: Cytomegalovirus in Pregnancy
Dealing with cytomegalovirus (CMV) can be vexing for everybody involved, but a recent paper may help with the management and counseling of patients infected with this virus at different times before and during pregnancy. -
Updates By Carol A. Kemper, MD, FACP
The number of infants born with HIV-infection in the United States reached its peak in 1991 with about 1650 HIV-infected infants, at which point the implementation of prevention guidelines resulted in a rapid reduction in neonatal infection. -
Clinical Briefs in Primary Care supplement
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Pharmacology Watch: Statins and the Risk of Diabetes
In this issue: Statins and diabetes risk; new treatment guideline for diabetes; new pertussis vaccine recommendation; antibiotics and rhinosinusitis; fluoroquinolones and cystitis; and FDA actions.