Hospital Medicine Alert – November 1, 2016
November 1, 2016
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Safely Centralized Telemetry Off-site in a Multi-hospital System
SYNOPSIS: The hospitals in this study outsourced their cardiac telemetry to an off-site central monitoring center without an increase in adverse events.
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Growing Threat of Pyelonephritis Caused by Antibiotic-resistant Escherichia coli
SYNOPSIS: In patients with acute pyelonephritis due Escherichia coli presenting to one of 10 emergency departments, the prevalence of fluoroquinolone resistance ranged from 6.3% to 19.9%, and the prevalence of extended-spectrum beta-lactamase production was 2.6% to 12.2%. Of those patients with resistant organisms, more than 50% received inactive empiric antibiotics.
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Influence of Sacubitril/Valsartan on 30-day Readmission After Heart Failure
SYNOPSIS: Compared with enalapril, treatment with sacubitril/valsartan is more effective in reducing 30-day readmissions for any cause following discharge from congestive heart failure hospitalization.
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Noninvasive Ventilation Delivered Via Helmet May Decrease Intubation Rates
SYNOPSIS: In this single-center, randomized, clinical trial, among patients suffering from acute respiratory distress syndrome, the use of helmet noninvasive ventilation was associated with a reduction in intubation rates, ICU length of stay, and hospital and 90-day mortality.
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Heart Failure with Recovered Ejection Fraction: A Distinct Phenotype
SYNOPSIS: Patients suffering from systolic heart failure who subsequently improve their ejection fraction experience a more favorable clinical course compared to those presenting with persistently reduced ejection fraction or heart failure with preserved ejection fraction.
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Ticagrelor vs. Aspirin: Post-TIA and Stroke
The first 90 days after a transient ischemic attack or ischemic stroke is a high-risk period for recurrence of cardiovascular thrombotic events. Even with aspirin treatment, recurrences occur in as many as 10-15% of patients.