Hospital Medicine Alert – March 1, 2006

March 1, 2006

• Diabetic Foot Infections: Culture Results from Bone Biopsy and Swab Specimens

  eventy-six patients with diabetic foot osteomyelitis underwent surgical bone biopsy for culture had bone culture results compared to swab culture results.

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• Toxic Shock Syndrome After Medical Abortion

  Rare cases of fatal toxic shock syndrome associated with Clostridium sordellii have been reported; clinicians are urged to be aware of warning signals.

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• Forgotten Hazards of Sedatives

  This case series and prospective observational study describe propylene glycol toxicity in patients receiving IV benzodiazepines.

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• Anticoagulation for Atrial Fibrillation in Acute MI

  In daily clinical practice, OAC was only given to a minority (30%) of AMI patients with AF, despite the fact that OAC was associated with a 29% relative and 7% absolute reduction in 1-year mortality ...

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• Prophylactic Amiodarone After Heart Surgery

  Atrial fibrillation remains a common and vexing problem after cardiac surgery.

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• Aminophylline in COPD Exacerbations: Just Say No

  In a well-designed double-blind placebo-controlled clinical trial in COPD patients admitted with an exacerbation, aminophylline produced no clinically relevant benefit but increased the incidence of nausea.

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