OB/GYN Clinical Alert – May 1, 2023

May 1, 2023

• Retrospective Cohort Analysis of Perinatal Outcomes Following Bariatric Surgery

  In a retrospective study of a racially and ethnically diverse cohort in 2012-2018, patients with a live birth after bariatric surgery had a lower risk of preeclampsia, gestational diabetes or impaired fasting glucose, and having a large-for-gestational-age infant — but a higher risk of having a small-for-gestational-age infant — relative to matched controls who did not have bariatric surgery before their live birth.

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• Diagnosis of Obstructive Sleep Apnea During Pregnancy

  Obstructive sleep apnea is associated with several adverse maternal and fetal outcomes.

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• CIN2 Is More Likely to Progress if HPV 16 Is Present

  This study examined rates of cervical intraepithelial neoplasia grade 2 (CIN2) regression and progression among women ages 25-30 years and found that regression rates varied by human papillomavirus (HPV) genotype: 51% regression and 47% progression in HPV 16 infections compared to 83% regression and 16% progression for infections with other HPV types.

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• Does Topiramate Decrease the Efficacy of Oral Contraceptives?

  In this retrospective cohort study, women taking low-dose topiramate (< 200 mg per day) and oral contraception did not have more contraceptive failures compared to women taking other headache remedies (propanolol, metoprolol, amitriptyline, venlafaxine, or verapamil), with an adjusted rate difference of 0.00 (95% confidence interval, -0.3, 0.3).

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• OB/GYN Clinical Alert Celebrates 40 Years

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