OB/GYN Clinical Alert – April 1, 2023

April 1, 2023

• Is Vaginal Carbon Dioxide Laser an Effective Treatment for the Genitourinary Syndrome of Menopause?

  In this double-blinded, randomized controlled trial, fractional carbon dioxide vaginal laser was no better than sham laser in improving Female Sexual Function Index scores among 72 breast cancer survivors on aromatase inhibitors over a six-month period.

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• Do Anti-Müllerian Hormone Levels Decline More Rapidly After Hysterectomy with Ovarian Conservation?

  In this multi-site, community-based study, anti-Müllerian hormone levels did not decline more rapidly among patients who underwent hysterectomy with ovarian conservation compared to patients who experienced natural menopause.

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• The Efficacy of Prenatal Patients Using a Mindfulness App

  This randomized trial conducted early in the pandemic with women from an obstetric and gynecologic practice found use of a mobile app promoting mindfulness practice (such as meditation) was associated with a decrease in perceived stress, self-reported anxiety and depression, and sleep disturbance in the intervention group.

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• Opioid Use Disorders During Pregnancy

  Currently, the United States faces an enormous opioid crisis, with opioid use disorder (OUD) being the leading cause of morbidity and mortality in some states. The number of pregnant people with OUD increased from 1.5 cases per 1,000 hospital deliveries to 6.5 cases per 1,000 hospital deliveries in the United States between 1999 and 2014, a more than four-fold rise. Proper identification and management of pregnant and postpartum people with OUD is crucial.

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