Internal Medicine Alert – June 15, 2023
June 15, 2023
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Cardiovascular Outcomes with Bempedoic Acid, a New Statin Alternative
A trial of bempedoic acid vs. placebo for statin-intolerant patients showed bempedoic acid significantly lowered LDL cholesterol levels and prevented more major adverse cardiovascular events after a median follow-up of 41 months. Although nonserious side effects were numerically higher for those on bempedoic acid, serious adverse events were not significantly different from placebo.
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Sitting, Standing, and Walking: The Effect on Cardiometabolic Markers
The authors of this meta-analysis explored the effects of interrupting sitting with either light-intensity walking or standing. They found light-intensity walking was associated with the most significant effect on several markers of cardiometabolic health.
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Focused Ultrasound Ablation of the Subthalamic Nucleus for Parkinson’s Disease Tremor
Researchers demonstrated the long-term efficacy and safety of unilateral MRI-guided high-frequency ultrasound subthalamotomy for Parkinson’s disease patients with motor fluctuations and dyskinesia three years after the procedure.
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Respiratory Syncytial Virus Vaccine, Adjuvanted (Arexvy)
Arexvy can be administered to prevent lower respiratory tract disease caused by respiratory syncytial virus in patients age 60 years and older.
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A Hidden Rhythm
The only clinical information available for this tracing is that the ECG was obtained from an older woman. Without any other background, where should we go from here?