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ABSTRACT & COMMENTARY

Oral Penicillin Challenge Found to Be Noninferior to Skin Testing Followed by Oral Challenge in Low-Risk Patients with Reported Penicillin Allergy

A multicenter, randomized clinical trial that compared direct oral penicillin challenge in low-risk patients to skin testing followed by oral challenge found no significant differences. Direct oral penicillin challenge appears to be a safe and effective way to delabel a penicillin allergy.