Articles Tagged With: Sepsis
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Using Procalcitonin to Limit Antibiotic Treatment for Sepsis Reduces Infection-Related Adverse Events
By shortening the duration of antibiotic therapy, a procalcitonin-guided protocol decreased the rate of infection-associated adverse effects, decreased costs, and reduced mortality in patient with sepsis.
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Confusing Presentation Could Result in Successful Missed Sepsis Claims
Despite recent emphasis on early sepsis intervention, little is known on exactly what symptoms these patients experience when presenting to EDs — and how frequently. This knowledge is important for educating the public about what symptoms may portend a diagnosis of sepsis, as well as educating clinicians about what symptom profiles they should be aware of when it comes to diagnosing sepsis.
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American Heart Association Calls for End to Structural Racism
Group “declares its unequivocal support of antiracist principles” in a recent presidential advisory.
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Nurse Navigator Role Helps Reduce 30-Day Readmissions
A program that used nurse navigators with heart failure patients cut its 30-day readmission rate in half and provided more thorough follow-up care in transitioning patients home.
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Corticosteroid Bursts and Subsequent Sepsis
Short-term (< 14 days) administration of oral corticosteroids is associated with an increased risk of adverse events, including an approximately two-fold risk of sepsis.
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Maternal Sepsis: Risk Factors that Could Lead to Postpartum Readmission
In this analysis of California deliveries between 2008 and 2011, risk factors for maternal readmission for sepsis were found to include preterm birth, hemorrhage, obesity, and a primary cesarean delivery.
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Considerations and Concerns with Vitamin C in Sepsis and Septic Shock
Sepsis remains a major healthcare problem associated with significant morbidity and mortality. Roles for hydrocortisone, ascorbic acid (vitamin C), and thiamine (HAT therapy) as potential adjuvants remain controversial.
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ORANGES and ACTS Trials: No Mortality Benefit with Ascorbic Acid, Thiamine, and Hydrocortisone in Septic Shock Patients
Two double-blinded, placebo-controlled, randomized trials involving 337 patients (ORANGES, n = 137; ACTS, n = 200) with sepsis and septic shock have shown that administration of ascorbic acid, thiamine, and hydrocortisone did not reduce organ dysfunction or improve overall mortality. However, both trials showed that this combination therapy was effective in reducing the time to achieve shock resolution or shock-free days.
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Sepsis Outcomes Improve, But Not at Minority-Serving Hospitals
ICU deaths declined 2% steadily annually at non-minority hospitals, according to a recent report. This was not true of minority-serving hospitals. Those hospitals also reported longer lengths of stay and more critical illness than non-minority hospitals.
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A Combination of Both SIRS and SOFA Scores Enhances Recognition of Sepsis in the Emergency Department
Compared with either score alone, using both SIRS and SOFA scores led to earlier and more complete recognition of sepsis in patients presenting to the emergency department.