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  • Extensively Drug-Resistant Shigella on the Rise

    The prevalence of Shigella resistant to azithromycin, ciprofloxacin, ceftriaxone, trimethoprim-sulfamethoxazole, and ampicillin is increasing.

  • Delusional Infestation

    Delusional infestation, previously known as delusional parasitosis, is a condition with which patients believe that their bodies are infested with abnormal living organisms or non-living substances. Many patients can recover with a good therapeutic clinician-patient relationship and, usually, the use of risperidone, aripiprazole, or olanzapine.

  • Mortality in Sepsis Patients Treated with Piperacillin-Tazobactam vs. Cefepime

    A retrospective cohort study that included more than 7,000 patients with sepsis and no clear indication for anti-anaerobic coverage found receipt of piperacillin-tazobactam was associated with higher mortality and increased duration of organ dysfunction compared to cefepime.

  • The Cath was “Clean!”

    The featured electrocardiogram was obtained following successful resuscitation from cardiac arrest. Although echo done soon after showed akinesis of the anterior wall, no significant coronary narrowing was seen on cardiac catheterization. Can you explain? What is this phenomenon called?

  • Donanemab-azbt (Kisunla)

    The U.S. Food and Drug Administration has approved the third anti-amyloid beta monoclonal antibody for the treatment of Alzheimer’s disease, following aducanumab and lecanemab.

  • Dengue Is Surging, Including in the Americas

    Dengue is surging, and cases have been acquired in the United States, including in Puerto Rico and Florida.

  • CVD Risk from Ketogenic Diets

    A recent analysis of the UK Biobank data found that subjects on a low-carbohydrate, high-fat diet had higher levels of low-density lipoprotein cholesterol and apolipoprotein B, and an increase in incident major adverse cardiovascular events over a 12-year follow-up than subjects on a standard diet.

  • Comparing Antidepressants’ Effects on Weight Gain

    This observational study finds that, compared to sertraline, six-month weight gain is higher in patients prescribed other antidepressants in the same category (paroxetine, citalopram, escitalopram) as well as in patients prescribed duloxetine and venlafaxine, similar in patients prescribed fluoxetine, and lower in patients prescribed bupropion.

  • Concussion Assessment in the Emergency Department with an Emphasis on Sports-Related Injury

    The body of research regarding concussions has broadened dramatically in recent years. This expanded medical knowledge has led to changes in the recommended treatment of concussion. It is important for emergency medicine physicians to be well versed in the recognition and management of concussion in the emergency department, as well as potential complications and long-term sequelae of this condition.

  • Is Endomyocardial Biopsy Still Necessary if Cardiac MRI Is Available?

    A multicenter registry study in Europe of patients with suspected myocarditis has shown that, compared to cardiac magnetic resonance imaging, endomyocardial biopsy still is the gold standard, and lower ejection fraction and need for immunosuppressant drugs predicted a worse outcome.