Articles Tagged With:
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Electrodiagnostic Features of Vasculitic Neuropathy
Electrophysiological studies of vasculitic neuropathy indicate that the best discriminators of vasculitis vs. other axonal neuropathies are the side-to-side differences between the same bilateral nerves. When the diagnosis is uncertain, nerve biopsy may be definitive.
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Insulin Resistance at the Blood-Brain Barrier in Alzheimer’s Disease
Alterations in cerebrovascular insulin receptor isoform levels are associated with Alzheimer’s disease pathology and cause deficits in insulin signaling at the level of the blood-brain barrier.
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Leriglitazone for the Treatment of Adrenomyeloneuropathy
A 96-week trial of leriglitazone to slow the progression of symptoms in adrenomyeloneuropathy did not meet the primary endpoint. However, post-hoc analyses revealed a beneficial effect in patients treated earlier in their disease course.
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Self-Treatment of Recurrent Benign Paroxysmal Positional Vertigo
Using a cell phone-based app, self-treatment of recurrent benign positional paroxysmal vertigo was feasible and effective in most patients.
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A Population-Based Study of Progressive Multifocal Leukoencephalopathy
In this population-based cohort study of 584 cases of progressive multifocal leukoencephalopathy (PML), predisposing conditions with the highest risk of PML were human immunodeficiency virus (HIV) infection, hematological malignancies, chronic inflammatory disease, solid organ transplantation, solid malignancies, and primary immune deficiency. The one-year mortality rate was 38.2% for all cases of PML. Factors independently associated with higher mortality rate were older age, male gender, and immunosuppressive diseases, such as hematological malignancies, solid neoplasms, and HIV.
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Concerns and Complications of Measles and Mumps
Decreased vaccine coverage against diseases such as measles and mumps has led to new vulnerabilities in pediatric population health. Thus, the astute practitioner should be vigilant and ready to recognize and diagnose these infections.
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Worker Shortage, Pandemic Make Drug Diversion Easier
Drug diversion can happen quickly as healthcare workers move from one facility to another, enabled by lax reporting systems and hospital disincentives to alert patients and raise liability issues. Diverters may slip through cracks in oversight by medical and nursing boards as they move to other facilities and are lost to follow-up.
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Multistate Drug Diverter’s Plea Denied, Faces 29 More Years
When it comes to discussion and analysis of drug diversion, David Kwiatkowski is the elephant in the room. More aptly, he is in a Florida federal prison cell. A hepatis C virus carrier, Kwiatkowski was sentenced to 39 years in prison in 2013 for infecting a string of victims with HCV as he diverted drugs from multiple hospitals in eight states. Tracking back through this trail of tears, federal officials with the Department of Health and Human Services tallied 45 HCV-infected patients, two of whom died.
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FDA Streamlining COVID-19 Shot to a Single Formula
Conceding the various vaccine doses and multiple boosters have caused considerable confusion, and some degree of pandemic apathy, the FDA’s Vaccines and Related Biological Products Advisory Committee unanimously voted to simplify and “harmonize” the process by switching to a single vaccine formula to be administered annually for most people.
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Striking Nurses Receive More Staffing, Raises
Around 7,000 hospital nurses in New York City held a three-day strike that led to hospitals conceding to their demands for higher pay and improved staffing. Winning such a victory when staff shortages are widely reported could result in other hospitals following suit, as nurses demand fair treatment, full staffing, and equitable compensation after three years of fighting a pandemic.