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The use of biomarkers from the CSF, as well as newer PET imaging ligands, allow for an accurate diagnosis in patients who have a syndrome of posterior cortical atrophy.
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In this non-randomized comparative trial, dorsal (posterior) decompressive spinal surgery resulted in longer lengths of stay and higher costs compared to ventral (anterior) surgery.
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Two new drugs for treatment of hepatitis C; NSAIDs and myocardial infarction risk; AIM-HIGH clinical trial stopped; and FDA actions.
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Crest failed to demonstrate any significant differ-ence in the primary endpoint (composite of stroke, myocardial infarction, or death during the 4-year follow-up period) between carotid artery stenting (CAS) and carotid endarterectomy (CEA) in patients with symptomatic or asymptomatic carotid artery stenosis.
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Entrapment neuropathies are not more common in the setting of chronic inflammatory demyelinating neuropathy and suggest a surgically treatable lesion.
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Biomarkers for Parkinson's disease and related neurodegenerative diseases occur frequently in patients with idiopathic REM sleep behavior disorder. These include impairment of olfactory and color discrimination, and abnormalities in cerebral blood flow.
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Patients originally on interferon beta-1a in the TRANSFORMS study were re-randomized to either 0.5 or 1.25 mg of fingolimod. There was a reduction in relapse rate and MRI activity in patients that switched to fingolimod without an increase in severe adverse events.
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Variant Creutzfeldt-Jakob disease usually presents with subtle psychiatric symptoms and there is usually a significant delay in diagnosis.