-
Antihypertensive treatment reduces the incidence of headache compared to placebo, but the magnitude of the effect differs between drug classes independent of the magnitude of blood pressure reduction. Dysautoregulation in the anterior and posterior circulation is associated with migraine with aura.
-
In a post-hoc analysis, rasagiline, as an adjunct to levodopa, is both efficacious in reducing "off" time and well-tolerated in individuals older than 70 years with moderate-to-advanced Parkinson's disease.
-
-
Necrotizing myositis is a newly described inflammatory myopathy that has an autoimmune etiology and may be associated with anti-signal recognition particle autoantibodies.
-
Statins and diabetes risk; new treatment guideline for diabetes; new pertussis vaccine recommendation; antibiotics and rhinosinusitis; fluoroquinolones and cystitis; and FDA actions.
-
Preliminary trials of low-dose intranasal insulin suggest a possible benefit that warrants further investigation.
-
REM behavior disorder can be reliably diagnosed using a simple bed-partner questionnaire and its presence is a risk factor for a future neurodegenerative disease.
-
The clinicopathological features of nine patients with pure autonomic neuropathy, with or without antiganglionic acetylcholine antibody, were assessed. There was considerable variability in the clinical manifestations, course, unmyelinated nerve fiber loss, and response to therapy.
-
Isoflurane causes mitochondrial disruption and apoptosis in neuronal and hippocampal cells, and decreases memory consolidation in mice. Such effects are not seen with desflurane. This may impact selection of anesthetic agents for patients with Alzheimer's disease undergoing surgical procedures.
-
Based on a retrospective analysis of 77 patients with monophasic and recurrent inflammatory spinal cord disease, the authors report significantly lower vitamin D levels in patients with recurrent disease.