Articles Tagged With: Neurology
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Indications for Reduced-Dose Direct Oral Anticoagulants
A subgroup analysis of the ENGAGE-AF TIMI 48 study of edoxaban 60 mg/day vs. 30 mg/day compared to warfarin in patients with atrial fibrillation of the group 80 years of age or older has shown that 30 mg/day results in less major bleeding without a concomitant increase in stroke risk compared to 60 mg/day or warfarin.
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Anchoring Alzheimer’s Disease Along an Amyloid Timeline
In 601 individuals from Wisconsin-based cohorts with amyloid-beta and tau positron emission tomography scans, the magnitude and topographical spread of tau pathology increased with longer duration of amyloid-beta positivity, and the cognitive decline was steepest in those with the longest duration of amyloid-beta positivity and elevated entorhinal tau.
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Donanemab-azbt (Kisunla)
The U.S. Food and Drug Administration has approved the third anti-amyloid beta monoclonal antibody for the treatment of Alzheimer’s disease, following aducanumab and lecanemab.
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Rapid Reversal of Anticoagulation Reduces Mortality from Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is the deadliest type of stroke. ICH associated with anticoagulation carries an even higher mortality. Serial imaging studies have demonstrated that there is significant hematoma enlargement during the first few hours after arrival at the hospital, and this also portends a poor outcome.
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Caring After COVID: Is Brain Impairment After Severe COVID-19 Worse Than Other Diseases?
The authors of this prospective cohort study with matched controls found that long-term brain health following severe COVID-19 hospitalization was impaired but was similar to hospitalization from other severe diseases.
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Can Internet Use Prevent Dementia?
In an ongoing longitudinal survey of a nationally representative sample of dementia-free adults age 50 to 64.9 years, regular internet users experienced approximately half the risk of dementia compared with non-regular users.
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Healthy Lifestyles Can Help Reduce Cognitive Decline
In a population-based, prospective cohort study of 29,000 Chinese adults, researchers found healthy lifestyle was associated with slower memory decline, even in the presence of the apolipoprotein E4 allele.
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Poor Cardiovascular Health a Predictor for Premature Brain Aging
Worse cardiovascular health at age 36 years can predict worse brain aging and associated cognitive problems later in life.
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No Liability for Telemedicine Company or Hospital Over Stroke Treatment
This case confirms the importance of timely treatment and how providers can defend against claims of failure to provide such treatment. Frequently, a patient’s condition requires time-sensitive treatment, and the failure to do so may constitute medical malpractice if a similar physician under such circumstances would provide that timely care.
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Neurologists Look Beyond Traditional Addiction Treatment Techniques
Researchers explore why some patients were suddenly no longer craving nicotine after the appearance of a brain lesion.