Articles Tagged With:
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Lebrikizumab-lbkz Injection (Ebglyss)
The U.S. Food and Drug Administration has approved a humanized monoclonal antibody that targets interleukin-13 for the treatment of moderate-to-severe atopic dermatitis.
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Diagnostic Uncertainty in Community-Acquired Pneumonia
A national retrospective cohort study from the Veterans Administration found a high rate of diagnostic discordance for patients admitted and discharged for community-acquired pneumonia (CAP). Improvement in the diagnosis of CAP is needed.
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Understanding Myocarditis, COVID-19 Infection, and COVID-19 Vaccines
Although myocarditis is rare, interest has increased in recent years because of the COVID-19 pandemic and COVID-19 vaccinations both being associated with its development. This review article will trace the history of myocarditis from the pre-COVID-19 era to the present day.
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A Review of Throat Infections: Low-Acuity Disease
Sore throats are common pediatric chief complaints, with etiologies ranging from thrush to epiglottitis. All clinicians must be familiar with the diversity of causes from benign to life-threatening in order to decrease morbidity and mortality with a timely diagnosis.
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Pediatric Trauma 2025 Is Here!
The latest installment in an award-winning series, Pediatric Trauma 2025: Quality Care for Serious Pediatric Injuries facilitates excellence by covering the latest scientific information on caring for children who present with traumatic injuries. Perfect for pediatric trauma programs, this book provides 18 hours of pediatric trauma-specific CME/CE credits, meeting the yearly requirements for trauma-certified professionals.
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Eculizumab for Treating Aquaporin-4 Antibody-Positive NMOSD
In this retrospective study of a cohort of aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (NMOSD) patients treated with eculizumab, the authors reported efficacy with decreasing relapse rate, magnetic resonance imaging changes, and disability outcomes, but cautioned about the risk of serious infections.
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A microRNA Diagnostic Biomarker for ALS
A specific pattern of eight micro ribonucleic acids (microRNAs) has been shown to differentiate patients with amyotrophic lateral sclerosis (ALS) from those with primary lateral sclerosis, Parkinson’s disease, and healthy controls. It remains to be determined if these differences will continue throughout the course of the disease.
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Repeated Head Trauma May Lead to Parkinsonism in Patients with CTE
Repeated head injury from years of contact sports play in men with confirmed chronic traumatic encephalopathy (CTE) may cause pathological changes in the substantia nigra that lead to parkinsonism in a subset of patients with CTE.
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Genetic Testing for Patients with Parkinson’s Disease
In this large scale, international study of Parkinson’s disease (PD) patients, approximately 15% of participants were found to have a positive PD-related genetic variant, most commonly in the GBA1 and LRRK2 genes.
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MRI-Guided Focused Ultrasound Thalamotomy for Treating Essential Tremor
This open-label study demonstrated the safety and efficacy of staged bilateral magnetic resonance imaging-guided focused ultrasound thalamotomy for bilateral essential tremor with excellent efficacy rates at one year. Most adverse events were mild, but greater real-world experience is needed to understand its true safety profile.