Articles Tagged With:
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PFO Closure Review Shows High Proportion of Off-Label Use
In this retrospective cohort study using administrative data from a U.S. payor source, only 58.6% of patients undergoing patent foramen ovale closure had the procedure done for the approved indication of stroke or systemic embolism. A significant proportion of patients were outside the recommended age range.
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Do Patients Feel Better After Tricuspid Valve Clipping?
A further analysis of the quality-of-life parameters in a trial of tricuspid transcatheter edge-to-edge repair (T-TEER) in patients with severe symptomatic tricuspid regurgitation vs. medical therapy alone has shown that T-TEER is associated with significant benefits in physical functioning and quality of life that are sustained for one year and were proportional to the magnitude of regurgitation reduction.
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Does Anyone with Severe Aortic Stenosis Not Benefit from TAVR?
A single-center, retrospective study of low-flow low-gradient aortic stenosis patients has shown that a gradient < 20 mmHg identifies a high-risk group because of significant comorbidities that may not benefit from transcutaneous aortic valve replacement.
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Teen Pregnancies in the ED Part 1: First Trimester
This article is the first of a two-part series that focuses on an important emergency medicine topic — teenage pregnancy. In this first part, the author focuses on the unique features that affect diagnosis and management of pregnancy in adolescence. Part two will focus on obstetrical emergencies in pregnant teenagers.
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Evaluation and Management of Neck Trauma
The neck is a complex region that may have injuries that range from minor to life-threatening. An understanding of the anatomy and potential injuries is essential to optimize patient care and outcomes.
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Imported Gestational Malaria
Pregnant women can develop malaria in non-endemic areas, even when they are far removed from malaria exposure both geographically and temporally.
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Zuranolone Therapy for Depression in the Postpartum Period
Zuranolone was well tolerated and resulted in substantial improvement of depressive symptoms in the postpartum period, suggesting that it may be a promising new oral therapy for postpartum depression.
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How Does the Genitourinary Syndrome of Menopause Affect Patients?
This analysis of baseline questionnaire responses from 302 individuals enrolled in the MsFLASH Vaginal Health Trial demonstrated that the most commonly reported symptoms were vaginal dryness (94%), pain with vaginal penetration (84%), vulvovaginal pain and soreness (76%), and vulvovaginal irritation (73%). The symptom most often rated severe was pain with vaginal penetration (40%).
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Mifepristone as a Treatment Option for Adenomyosis
This multicenter, placebo-controlled, double-blind randomized clinical trial was conducted in 10 hospitals in China and enrolled 134 patients with diagnosed adenomyosis to evaluate mifepristone as an effective treatment for adenomyosis pain symptoms. Among the intervention group, 98.1% had total remission of adenomyosis pain symptoms as well as improved secondary outcomes with no serious adverse events. Mifepristone is promising for treating pain from adenomyosis.
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Nearly Half of ED Patients Reported Health-Related Social Needs