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Ethics Issues for Young Adults Vary Depending on Setting
As a medical student at the University of Michigan, Samantha Lyons, MD, HEC-C, regularly attended both pediatric and adult ethics committee meetings. Lyons noticed that for young adults, different approaches were used based on whether the patient presented to the pediatric or adult setting. In general, pediatric care was more family-oriented, whereas adult care placed more emphasis on patients being autonomous and independent.
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Many Hospital Websites Lack Information on Clinical Ethics Consultation Services
Many patients and family members, and even some clinicians, are unaware of the basics of what ethicists do or even how to contact them. However, many ethics services do not post any information at all on their institutional websites, a recent study found.
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An ECG in Disguise?
The electrocardiogram (ECG) in the figure was recorded from an older man following a bradycardic and hypotensive episode. What ECG diagnosis is suggested by this tracing?
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Epinephrine Nasal Spray (Neffy)
The U.S. Food and Drug Administration has approved epinephrine nasal spray for the emergency treatment of allergic reactions, including anaphylaxis. It was granted a fast-track designation and will be distributed by ARS Pharmaceuticals as Neffy.
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Indications for Reduced-Dose Direct Oral Anticoagulants
A subgroup analysis of the ENGAGE-AF TIMI 48 study of edoxaban 60 mg/day vs. 30 mg/day compared to warfarin in patients with atrial fibrillation of the group 80 years of age or older has shown that 30 mg/day results in less major bleeding without a concomitant increase in stroke risk compared to 60 mg/day or warfarin.
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Anchoring Alzheimer’s Disease Along an Amyloid Timeline
In 601 individuals from Wisconsin-based cohorts with amyloid-beta and tau positron emission tomography scans, the magnitude and topographical spread of tau pathology increased with longer duration of amyloid-beta positivity, and the cognitive decline was steepest in those with the longest duration of amyloid-beta positivity and elevated entorhinal tau.
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Sweating for Sleep: Examining Evening Exercise and its Effects on Sleep Duration
This small, randomized crossover trial demonstrates that short, repetitive bouts of early evening exercise lead to an increase in total sleep time compared to prolonged sitting.
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Multicomponent Breastfeeding Interventions in Women with a Body Mass Index > 25
The study found no statistically significant differences in breastfeeding outcomes between the intervention and control groups at various postpartum time points, although the intervention group received more hospital-based support, while the control group sought more private lactation support.
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What Do Patients Know About Anti-Müllerian Hormone Testing?
In this randomized, controlled, online questionnaire trial, participants who received evidence-based information about anti-Müllerian hormone (AMH) testing had lower interest in getting an AMH test (mean difference, 1.05; 95% confidence interval, 0.83-1.30) than individuals who viewed the control information from a direct-to-consumer website.
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Rethinking Endometrial Thickness Thresholds that Prompt Endometrial Biopsy to Rule Out Endometrial Cancer
In a retrospective review of 1,494 pre- and postmenopausal Black individuals who underwent transvaginal ultrasonography, 24 of 210 individuals (11.4%) with endometrial cancer had an endometrial thickness lower than the threshold for undergoing biopsy to detect cancer.