Articles Tagged With: brain
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Tau as a Biomarker of Acute and Chronic Traumatic Brain Injury
The ongoing search for reliable biomarkers of traumatic brain injury repeatedly has demonstrated the reliability of using plasma phosphor-tau levels to help distinguish injury from normal, and severe injury from mild injury.
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Taste, Smell, and the Insular Cortex
Olfaction and taste appear to be localized in the insular cortex with bilateral representation.
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EEG-based Metrics After Severe Brain Injury
In this cohort study of 104 patients with disorders of consciousness, the authors demonstrated a strong correlation between EEG-based metrics and clinical diagnosis using quantitative behavioral scales, brain metabolism as measured by PET, and clinical outcomes at one year.
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Mild Traumatic Brain Injury Induces Altered Sleep and Impaired Memory
Traumatic brain injury may induce a chronic state of altered sleep with impaired memory consolidation and mood disorders.
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Electrical Brain Stimulation for Primary Progressive Aphasia
In this pilot study, transcranial direct current stimulation appeared to improve some aspects of verbal object identification and naming in a small number of patients with primary progressive aphasia.
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Association of Traumatic Brain Injury with Late-life Neurodegenerative Diseases
This study analyzed pooled clinical and neuropathological data of older adults free of dementia from three prospective cohort studies and found that traumatic brain injury with loss of consciousness was associated with risk for Lewy body accumulation, Parkinson’s disease, and progression of Parkinsonism, but not dementia, Alzheimer’s disease, neuritic plaques, or neurofibrillary tangles.
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Blood-Based Biomarkers in the Evaluation of Alzheimer’s Disease
At the present time, no blood-based biomarkers have been identified as reliable indicators of A-beta amyloid deposition in the brain.
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Treating Physician Did Not Violate Standard of Care for Failure to Treat Brain Swelling, Jury Finds
A 12-year-old girl was taken by ambulance to a hospital. She exhibited symptoms of hyperglycemia, abnormal respiration, and an accelerated heart rate. The physician in the emergency department treated her with insulin. Ten minutes later, the physician noted that the patient had acidemia (significant amounts of acid in the blood).
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Pediatric Head Injury
The impact of traumatic brain injury as a leading cause of death and morbidity in the pediatric population cannot be ignored, and significantly impacts any provider who cares for children.
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$21.9 M award in elective steroid injection procedure
A 54-year-old woman suffered from chronic and severe back pain, and she underwent an elective epidural steroid injection. While sedated, the patient’s airway became blocked, which resulted in oxygen deprivation for as long as 10 minutes. Multiple electronic monitors indicated that the patient was not breathing properly, but the physician continued the procedure. Emergency assistance was not called for more than an hour, and the physician failed to report to a subsequent treating hospital that the patient was deprived of oxygen for several minutes. The patient suffered severe brain damage, and she died six years after the procedure from complications related to the brain injury. The jury awarded the widower and estate $21.9 million in damages.